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Grape Seed Extract is a mixture of tannins and procyanidins (chains of catechins) that appears to exert anti-estrogenic effects and may enhance blood flow. Since ancient times, various parts of the grape have been used for medicinal purposes & Today, we know that grape seed extract contains oligomeric proanthocyanidin (OPC) an antioxidant that is believed to improve various health conditions like atherosclerosis, attention deficit disorder, cancer(prevention), chronic venous, insufficiency, collagen breakdown (prevention), dental caries (cavities), vision, retinopathy, varicose veins and endometriosis
Studies conducted in humans used in the range of 50-300mg Grape Seed extract daily for heart health purposes, while doses up to 600mg have been used with no reported side effects.