Alpha-Lipoic Acid (ALA) is a mitochondrial compound that is highly involved in energy metabolism. It is synthesized in the body and can be consumed through eating meat. It is also minimally present in some fruits and vegetables. In supplement form, it has shown benefit for various forms of oxidation and inflammation. These effects protect against heart diseases, liver diseases, diabetes, and neurological decline associated with aging. ALA is a potent anti-oxidant compound. It works with mitochondria and the body's natural anti-oxidant defenses. ALA is also seen as an anti-aging compound since it can reverse some of the oxidant damage related to the effects of aging.
|Is a Form Of||
Antiaging and Longevity
|Primary Function||Antioxidant and Anti-inflammatory|
|Also Known As||ALA, thioctic acid, 1, 2-dithiolane-3-pentanoic acid, ala, Tiolepta|
|Do Not Confuse With||Alpha-Linolenic Acid (omega-3 fatty acid)|
|Goes Well With||L-Carnitine|
Standard dosages of Alpha-Lipoic Acid (ALA) tend to be in the range of 300-600mg, with little differentiation based on whether the racemic mixture of ALA (S- and R- isomers) or Na-R-ALA results in higher blood levels.
ALA appears to be absorbed via transporter-related means, and despite being inherently fat-soluble it does not require dietary fatty acids to be absorbed from the gut. ALA supplementation can be taken in a fasted state.